The purpose of this systematic review was to compare corticosteroid injections with non-steroidal anti-inflammatory drug (NSAID) injections for musculoskeletal pain, stiffness, joint disorders and knee pain. METHODS: Medline, Embase, Web of Knowledge and Cochrane Central Register of Controlled Trials were searched, and information was derived from studies published between 1971 and February 2011, steroid meaning in hindi. Two authors independently assessed data integrity using standardised clinical grading and quality assessment procedures. Studies were included unless they failed to meet all of these criteria, steroid-pharm review. Data extracted were abstracted and then appraised critically, and if necessary disagreements were resolved by consensus, review steroid-pharm. RESULTS: The pooled analysis of randomized trials showed that: (a) corticosteroids are ineffective at relieving pain or decreasing the severity of pain, (b) NSAIDs are effective at relieving joint inflammation and reducing swelling, pain and stiffness, and (c) a corticosteroid placebo injection increases the risk of knee osteoarthritis (OA). CONCLUSIONS: Corticosteroids have a negligible impact on pain or joint pain and increase the risk of OA, steroid meaning in hindi. The risk of osteoarthritis (OA) for both NSAIDs and corticosteroids are also similar. Both groups are likely to benefit from joint supplementation with corticosteroids, testosterone for horses. Copyright © 2013 MRC PUBMED Ltd.
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